Genoprotective Effects of Aqueous Extracts of Rosa Canina L. Fruits on Ethyl Methanesulfonate-Induced DNA Damage in Drosophila Melanogaster

the effect of aqueous extract of garlic on formalin-induced pain in male rats

چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...

Hydroalcoholic and polyphenolic extracts of Ziziphus Jujuba Mill fruits prevent methyl methanesulfonate-induced DNA damage in HepG2 cells

Ziziphus jujuba Mill (ZJ), which has been extensively used by the Iranian traditional healers, belongs to the Ramnaceae family. This semitropical herb contains large quantities of polyphenols and flavonoids, which in turn reveal antioxidant, antibacterial, free radical scavengering, and several other pharmacological activities. The purpose of the present study was to evaluate the DNA damage pre...

Viability mutations induced by ethyl methanesulfonate in Drosophila melanogaster.

MUKAI and YAMAZAKI ( 1964, 1968) discovered a coupling-repulsion effect in Drosophila melanogaster. If mutant polygenes are located in only one of the homologous chromosomes, they show overdominance-this has been called the “coupling effect.” On the other hand, if mutant polygenes are located in both homologous chromosomes, they are deleterious in the heterozygous condition in comparison to the...

Protective effects of Rosa canina L fruit extracts on renal disturbances induced by reperfusion injury in rats.

INTRODUCTION This study aimed to investigate the effects of Rosa canina L fruit extracts on histological damages, oxidative stress, and functional disturbances induced by bilateral renal ischemia and reperfusion. MATERIALS AND METHODS Ischemia and reperfusion were induced on the kidneys of anesthetized male Sprague-Dawley rats. The rats in the reperfusion and Rosa canina groups were administe...

PROTECTIVE ROLE OF METHANOL EXTRACTS OF Gentiana asclepiadea L. AND G. cruciata L. AGAINST GENOTOXIC DAMAGE INDUCED BY ETHYL METHANESULFONATE